Rebuttal re Erroneous Analysis on Transgenic Insecticidal Crops - Loevei, Lovei

Rebuttal re Erroneous Analysis on Transgenic Insecticidal Crops.
Crop Biotech Update/ISAAA, Apr 17, 2009

An article by Lövei et al. (Transgenic insecticidal crops and natural enemies: a detailed review of laboratory studies, Environmental Entomology 38(2): 293-306 (2009)) purports that insect-protected crops based on the Cry proteins of Bacillus thuringiensis may have substantial negative impacts on non-target organisms.

A group of experts in this area strongly disagreed with this April, 2009 publication and felt that a rapid response was required but, because of production schedules of this bi-monthly journal, it could not accommodate a rapid rebuttal. Thus, A. M. Shelton and 14 colleagues published their Letter to the Editor in Transgenic Research (Setting the Record Straight: A Rebuttal to an Erroneous Analysis on Transgenic Insecticidal Crops and Natural Enemies).

Among the many concerns Shelton and colleagues describe in their rebuttal are the inappropriate and unsound methods for risk assessment that led Lövei et al. to reach conclusions that are in conflict with those of several comprehensive reviews and meta-analyses. Shelton summarized the concerns of the 15 authors by stating, "The Lövei et al. article advocates inappropriate summarization and statistical methods, a negatively biased and incorrect interpretation of the published data on non-target effects, and fails to place any putative effect into a meaningful ecological context." What was also troubling to this international group of 15 experts is the potential for the Lövei et al. article to be accepted at face value and impact some regulatory agencies.

Their rebuttal can be accessed using the following link: http://www.springerlink.com/content/q7hk642137241733/. The article is open access and freely available to all and is published as DOI: 10.1007/s11248-009-9260-5. It will be published in print form in the June issue of Transgenic Research.