Changes in time spent walking and the risk of incident dementia in
older Japanese people: the Ohsaki Cohort 2006 Study. Yasutake Tomata Shu
Zhang Kemmyo Sugiyama Yu Kaiho Yumi Sugawara Ichiro Tsuji. Age and
Ageing, Volume 46, Issue 5, September 1 2017, Pages 857–860,
https://doi.org/10.1093/ageing/afx078
The impact of
long-term changes in physical activity during adulthood in the context
of primary prevention of dementia has not been addressed previously.
Objective:
To study the relationship between changes in time spent walking after
middle age and incident dementia in older Japanese individuals.
[Methodology and results in the comments section.]
Conclusions:
These results suggest that maintaining a higher level of physical
activity after middle age may be a key strategy for prevention of
dementia in older age.
Keywords: walking, physical activity, dementia, older people, cohort study
Monday, October 9, 2017
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Methodology: We conducted a cohort study of 6,909 disability-free Japanese individuals aged ≥65 years who lived in Ohsaki City, Japan. In both 1994 and 2006, the individual amount of time spent walking per day was assessed using a self-reported questionnaire (<0.5 h, 0.5–1 h or ≥1 h). Based on these three categories of exposure at the two points, participants were categorised into nine groups according to changes in time spent walking. Data on incident dementia were retrieved from the public Long-term Care Insurance (LTCI) Database, in which participants were followed up for 5.7 years (between April 2007 and November 2012). The Cox model was used for estimating the multivariate-adjusted hazard ratios (HRs) of incident dementia.
ReplyDeleteResults: The 5.7-year incidence of dementia was 9.2%. Compared with persons who remained in the lowest category of time spent walking (<0.5 h/day in both 1994 and 2006), persons who remained in the highest category (≥1 h/day in both 1994 and 2006) had a significantly lower risk of incident dementia: the multivariate-adjusted HR (95% confidence intervals) was 0.72 (0.53 and 0.97).