Gender Differences in Stability of Brain Functional Connectivity: Female volunteers showed significantly higher temporal correlation coefficients than male volunteers, suggesting their brain FCs are more stable over time

F116. Gender Differences in Stability of Brain Functional Connectivity. Yicheng Long, Jie Lisa Ji, Alan Anticevic. Biological Psychiatry, 74th Annual Scientific Convention and Meeting, May 15, 2019, Volume 85, Issue 10, Supplement, Page S258. https://doi.org/10.1016/j.biopsych.2019.03.653

Background: Understanding gender differences of the brain’s intrinsic functional architecture may lead to a better understanding of the pathophysiology of many psychiatric disorders whose prevalence differs between genders. Recently, the dynamic brain functional connectivity (FC) has emerged as a major topic in resting-state functional magnetic resonance imaging (rs-fMRI) studies, and possible associations have been reported between several psychiatric disorders and the temporal stability of brain FCs. However, little is known about whether or not there is a gender difference in brain FC stability.
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Results: Female volunteers showed significantly higher temporal correlation coefficients than male volunteers [...], suggesting their brain FCs are more stable over time.
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Check also Gender differences in brain functional connectivity density. Dardo Tomasi, Nora D. Volkow. Human Brain Mapping, March 21 2011. https://doi.org/10.1002/hbm.21252

Abstract: The neural bases of gender differences in emotional, cognitive, and socials behaviors are largely unknown. Here, magnetic resonance imaging data from 336 women and 225 men revealed a gender dimorphism in the functional organization of the brain. Consistently across five research sites, women had 14% higher local functional connectivity density (lFCD) and up to 5% higher gray matter density than men in cortical and subcortical regions. The negative power scaling of the lFCD was steeper for men than for women, suggesting that the balance between strongly and weakly connected nodes in the brain is different across genders. The more distributed organization of the male brain than that of the female brain could help explain the gender differences in cognitive style and behaviors and in the prevalence of neuropsychiatric diseases (i.e., autism spectrum disorder).