Depersonalization is common in anxiety disorders; on a trait level, anxiety & depersonalization more frequently co-occur when people catastrophically misinterpret their symptoms or have lower emotional distress tolerance

French, Noah J., Jeremy W. Eberle, and Bethany Teachman. 2020. “Moderators of the Relationships Between State and Trait Anxiety and Depersonalization.” PsyArXiv. July 22. doi:10.31234/osf.io/63zrj

Abstract: Depersonalization is common in anxiety disorders, but little is known about the factors that influence co-occurring anxiety and depersonalization. We investigated trait moderators of the relationships between state and trait anxiety and depersonalization to better understand their co-occurrence and to identify potential points of intervention. Adults recruited on Amazon Mechanical Turk (N = 303) completed two computer tasks designed to increase variability in state anxiety and depersonalization as well as several self-report questionnaires. As hypothesized (preregistration: https://osf.io/xgazd/?view_only=56eba3dfb2b8454a97d3f66eb5217f7a), anxiety positively predicted depersonalization at both a state level, β = 0.43, 95% CI [0.39, 0.47], and a trait level, β = 0.60, 95% CI [0.51, 0.70]. Moreover, as hypothesized, the trait anxiety-trait depersonalization relationship was strengthened by greater anxiety sensitivity, β = 0.25, 95% CI [0.17, 0.34]; distress intolerance, β = 0.15, 95% CI [0.05, 0.25]; and negative interpretation bias for anxiety sensations (inverse transformed), β = -0.21, 95% CI [-0.30, -0.13], and for depersonalization sensations (inverse transformed), β = -0.27, 95% CI [-0.35, -0.19]. None of these hypothesized trait moderators significantly strengthened the state anxiety-state depersonalization relationship. These findings suggest that on a trait level, anxiety and depersonalization more frequently co-occur when people catastrophically misinterpret their symptoms or have lower emotional distress tolerance.