We present an integrative framework for mental disorders built on concepts from life history theory, and describe a taxonomy of mental disorders based on its principles, the Fast-Slow-Defense model

Del Giudice, Marco, and John D. Haltigan. 2020. “An Integrative Evolutionary Framework for Psychopathology.” PsyArXiv. October 2. doi:10.31234/osf.io/qv5nx

Abstract: The field of psychopathology is in a transformative phase, and is witnessing a renewed surge of interest in theoretical models of mental disorders. While many interesting proposals are competing for attention in the literature, they tend to focus narrowly on the proximate level of analysis and lack a broader understanding of biological function. In this paper, we present an integrative framework for mental disorders built on concepts from life history theory, and describe a taxonomy of mental disorders based on its principles, the Fast-Slow-Defense model (FSD). The FSD integrates psychopathology with normative individual differences in personality and behavior, and allows researchers to draw principled distinctions between broad clusters of disorders, as well as identify functional subtypes within current diagnostic categories. Simulation work demonstrates that the model can explain the large-scale structure of comorbidity, including the apparent emergence of a general “p factor” of psychopathology. A life history approach also provides novel integrative insights into the role of environmental risk/protective factors and the developmental trajectories of various disorders. After describing the main features of the FSD model and illustrating its application to the classification of autism and schizophrenia, we juxtapose it with the recent Hierarchical Taxonomy of Psychopathology (HiTOP). We highlight points of difference and similarity, and show how a functional approach helps resolve inconsistencies within a parsimonious account. The FSD model has great potential to further understanding of the development and expression of psychopathology across the lifespan.