Wednesday, February 10, 2021

Exercise-induced euphoria and anxiolysis are independent of direct occupancy of endogenous μ-opioid receptors binding; endocannabinoids are better candidates than endorphins to explain a runner's high in humans

Exercise-induced euphoria and anxiolysis do not depend on endogenous opioids in humans. Michael Siebers et al. Psychoneuroendocrinology, February 10 2021, 105173. https://doi.org/10.1016/j.psyneuen.2021.105173

Highlights

• Exercise-induced euphoria and anxiolysis are independent of direct occupancy of endogenous μ-opioid receptors binding.

• Running reduces anxiety levels in a human elevated plus-maze.

• Running stimulates the endocannabinoid system.

• Endocannabinoids are better candidates than endorphins to explain a runner's high in humans.

Abstract: A runner's high describes a sense of well-being during endurance exercise characterized by euphoria and anxiolysis. It has been a widespread belief that the release of endogenous opioids, such as endorphins, underlie a runner's high. However, exercise leads to the release of two classes of rewarding molecules, endocannabinoids (eCBs) and opioids. In mice, we have shown that core features of a runner's high depend on cannabinoid receptors but not opioid receptors. In the present study, we aimed to corroborate in humans that endorphins do not play a significant role in the underlying mechanism of a runner's high. Thus, we investigated whether the development of two core features of a runner's high, euphoria and reduced anxiety levels, depend on opioid signaling by using the opioid receptor antagonist naltrexone (NAL) in a double-blind, randomized, placebo (PLA)-controlled experiment. Participants (N=63) exhibited increased euphoria and decreased anxiety after 45 min of running (RUN) on a treadmill in a moderate-intensity range compared to walking (WALK). RUN led to higher plasma levels of the eCBs anandamide (AEA) and 2-arachidonoglycerol (2-AG). Opioid blockade did not prevent the development of euphoria and reduced anxiety as well as elevation of eCB levels following exercise. Moreover, the fraction of participants reporting a subjective runner's high was comparable in the NAL and PLA-treated group. Therefore, this study indicates that the development of a runner's high does not depend on opioid signaling in humans, but makes eCBs strong candidates in humans, as previously shown in mice.

Keywords: Endocannabinoidendorphinrunningexerciseanxietyeuphoria


‘She doesn’t think that happens’: When heterosexual men say no to sex

‘She doesn’t think that happens’: When heterosexual men say no to sex. Joni L  Meenagh. Sexualities, July 6, 2020. https://doi.org/10.1177/1363460720936460

h/t David Schmitt article explores three young people’s experiences of men saying ‘no’ to a woman’s request for sex within an ongoing relationship. In each of these instances the refusal was, to some extent, not respected

Abstract: Dominant understandings of men’s sexuality claim that men are always up for sex; as such, research on heterosexual men’s sexual refusals is sparse. Drawing on interviews conducted with young people (aged 18–23) living in and around Melbourne, Australia, this article explores three young people’s experiences of men saying ‘no’ to a woman’s request for sex within an ongoing relationship. In each of these instances the refusal was, to some extent, not respected. This presents a challenge to men’s masculinity which then needs to be redressed through compensatory manhood acts. This article explores how the truth claims of hegemonic masculinity and the male sexual drive discourse are reproduced through men and women’s social interactions, and unpacks the implications of men’s sexual refusals not being heard for sexual ethics education programmes.

Keywords Hegemonic masculinity, heterosexuality, male sexual drive discourse, sexual ethics, sexual refusals

Discussion and conclusion

Under the male sexual drive discourse men are expected to say yes to sex. Withinheterosexual relationships, women police the boundaries of appropriate masculin-ity. One way they do this is through not ‘hearing’ men’s sexual refusals. This is apotentially volatile position to be in: between feeling like they cannot say no to sexand having their refusal ignored, some men may not get the chance to learn how tonegotiate their own sexual boundaries. This is a problem, given the current pushtowards ‘sexual ethics’ and ‘respectful relationships’ type sexuality education pro-grams in Australia (Carmody, 2013; Fileborn, 2016; Our Watch, 2019).These programs seek to prevent violence against women by instilling in youngpeople an understanding of gendered power dynamics and behavioral tools forpromoting gender equity within their relationships; however, they do not yet go farenough in disrupting traditional gender norms. While these programs are a prom-ising development, research on young people’s experiences with theSex & EthicsViolence Prevention Programindicates that men improved in their understandingsof their partner’s needs, while women improved in caring for themselves(Carmody, 2013; Carmody and Overden, 2013). Looking at post-training feedbackfrom young men, assumptions that men are always up for sex are not challenged; instead, these young men have learned to better temper their sexual ‘drive’(Carmody, 2013).The stories told by John, Ash, and Berry indicate that traditional gendereddiscourses may be reproducing themselves in insidious ways through young peo-ple’s sexual negotiations. While this study reports on a small number of instances,it points to the need to look deeper at what is happening within young people’sromantic and sexual relationships. The sexual refusals discussed here all occurredamidst moments of emotional complexity within their relationships: John waswary of being hurt by Rachel; Ash was upset with his girlfriend’s apparent prior-itization of her career over their relationship; and Dave was trying to move onfrom his relationship with Berry. By requesting sex and ‘ignoring’ their partner’srefusal, these young women exercise power – albeit to limited effect – within theirrelationships. This has important implications for how we understand the gendereddynamics of relationship negotiation, and for promoting ethical frameworks ofsexual negotiation – most notably, that gendered power dynamics are complex andhegemonic norms can resurface in seemingly progressive ways.Sexual ethics education and violence prevention programs need to move beyondthe focus on negotiation based on women’s sexual pleasure and desire (seeCarmody, 2009). We expect women to be able to say both ‘no’ and ‘yes’ to sex,and we need to make this available to men as well. Without challenging anddisrupting the dominant discursive claim that men constantly desire sex andsexual attention, women – whether accidentally or deliberately – upholster themale sexual drive discourse and the gendered norms and double standards thatcome with it. We need to hear men’s stories of not wanting to have sex andunderstand their reasons for saying no in order to open space for more fluidtypes of masculinity to emerge. Without taking men’s experiences into account,we do a disservice to both women and men as we attempt to develop more ethicalsexual subject positions. However, we also need to remember that hegemonic mas-culinity is slippery, and what can seem like a fresh take on gendered norms mayjust be hegemonic masculinity playing out in a different way.

Limitations and directions for future research
This article has provided novel insights into heterosexual men’s experiences ofsaying ‘no’ to sex within their ongoing relationships, however there are anumber of limitations to this analysis. The research this study is drawn fromlooked at young people’s negotiation of their romantic and sexual relationshipsand did not explicitly seek to speak to heterosexual men about their sexual refusals.While the three stories presented here indicate that this is a potentially commonexperience, it is not possible to make inferences about the extent that it occurs.While there is a commonality in how these men then reasserted a more hegemonicmasculinity within their relationships, other men may respond differently – andother women may more readily ‘hear’ their partner’s sexual refusals. This is an arearipe for future research to explore, particularly given the implications for violence prevention programs. The potential for heterosexual men’s sexual refusals to gounheard, and for this to then trigger compensatory manhood acts which reasserttheir dominance, raises a number of questions about how best to work with menandwomen to promote respectful, ethical sexual negotiation.

Contemporary understandings of paleoanthropological data illustrate that the search for a line defining, or a specific point designating, “modern human” is problematic

The ripples of modernity: How we can extend paleoanthropology with the extended evolutionary synthesis. Marc Kissel  AgustÍn Fuentes. Evolutionary Anthropology: Issues, News, and Reviews; February 5 2021. https://doi.org/10.1002/evan.21883

Abstract: Contemporary understandings of paleoanthropological data illustrate that the search for a line defining, or a specific point designating, “modern human” is problematic. Here we lend support to the argument for the need to look for patterns in the paleoanthropological record that indicate how multiple evolutionary processes intersected to form the human niche, a concept critical to assessing the development and processes involved in the emergence of a contemporary human phenotype. We suggest that incorporating key elements of the Extended Evolutionary Synthesis (EES) into our endeavors offers a better and more integrative toolkit for modeling and assessing the evolution of the genus Homo. To illustrate our points, we highlight how aspects of the genetic exchanges, morphology, and material culture of the later Pleistocene complicate the concept of “modern” human behavior and suggest that multiple evolutionary patterns, processes, and pathways intersected to form the human niche.


500 Harlequin romance novel cover images, published from 1953 to 2014: Exploring the interactions among women’s evolved mating behaviors & sociocultural norm changes; increasing explicitness reflects permissiveness shifts

Fisher, M. L., & Meredith, T. (2021). Evolutionary and sociocultural themes in cover art on harlequin romance novels: A temporal analysis. Evolutionary Behavioral Sciences. Advance online publication. https://doi.org/10.1037/ebs0000258

Abstract: We analyzed over 500 Harlequin romance novel cover images, published from 1953 to 2014, to explore the interactions among women’s evolved mating behaviors and sociocultural norm changes. Examination of the covers reveals that over time there was an increasingly intimate focus on the couple (to the exclusion of other individuals), as represented by more reclining poses, physical interactions, and direct eye gazing. We contend, given that women have been the primary consumers of romance novels, that the covers address women’s evolved mate preferences and that the increasing explicitness of the imagery, in terms of sexuality and intimacy, reflects sociocultural shifts in permissiveness. Therefore, Harlequin cover art represents an innovative lens through which to examine both evolutionary and sociocultural forces pertaining to women’s evolved sexuality and mating interests. We discuss ideas for future research such as how the analysis of cover art could provide a case study in evoked cultural behaviors that result from shared psychological mechanisms produced in response to local environmental cues.


About 80% of those with a current sexual or romantic partner engaged in rough sex with them & most who engaged it liked it; bisexual women reported greater frequency & enjoyment, 54% enjoying it "very much"

What Is Rough Sex, Who Does It, and Who Likes It? Findings from a Probability Sample of U.S. Undergraduate Students. Debby Herbenick, Tsung-chieh Fu, Dubravka Svetina Valdivia, Callie Patterson, Yael Rosenstock Gonzalez, Lucia Guerra-Reyes, Heather Eastman-Mueller, Jonathon Beckmeyer & Molly Rosenberg. Archives of Sexual Behavior, Feb 9 2021. https://rd.springer.com/article/10.1007/s10508-021-01917-w

Abstract: Using data from an undergraduate probability sample, we aimed to: (1) describe the prevalence and demographic characteristics of students who reported having engaged in rough sex with their current partner; (2) assess which sexual behaviors students consider to be rough sex; (3) describe the frequency with which participants report engaging in rough sex as well as their reports of initiating and liking rough sex, in relation to gender and sexual identity; and (4) examine predictors of rough sex frequency. Participants were 4998 students randomly sampled from a large Midwestern university who completed a confidential Internet-based survey (2453 women, 2445 men, 41 gender non-binary, 36 transgender or other gender non-conforming identities). Within these, 1795 individuals who reported a romantic/sexual partner of at least 3 months responded to questions about engaging, liking, and initiating rough sex. The most common behaviors participants considered to be rough sex were choking, hair pulling, and spanking. Transgender and gender non-binary students more often endorsed behaviors as rough sex. Also, rough sex was conceptualized as multidimensional, with one cluster being more consistent with earlier conceptualizations of rough sex (e.g., hair pulling, spanking) and the second cluster including behaviors such as choking, slapping, punching, and making someone have sex. About 80% of those with a current sexual or romantic partner engaged in rough sex with them and most who engaged it liked it. Bisexual women reported greater rough sex frequency and enjoyment (54.1% indicated enjoying it “very much”). Implications for sexuality research and education are discussed.


There is little reason to think that accommodative monetary policy plays a significant role in reducing racial inequities in the way often discussed; on the contrary, it may well accentuate inequalities for extended periods

Bartscher, Alina K. and Kuhn, Moritz and Schularick, Moritz and Wachtel, Paul, Monetary Policy and Racial Inequality (January 2021). FRB of New York Staff Report No. 959, https://ssrn.com/abstract=3775699

Abstract: This paper aims at an improved understanding of the relationship between monetary policy and racial inequality. We investigate the distributional effects of monetary policy in a unified framework, linking monetary policy shocks both to earnings and wealth differentials between black and white households. Specifically, we show that, although a more accommodative monetary policy increases employment of black households more than white households, the overall effects are small. At the same time, an accommodative monetary policy shock exacerbates the wealth difference between black and white households, because black households own less financial assets that appreciate in value. Over multi-year time horizons, the employment effects are substantially smaller than the countervailing portfolio effects. We conclude that there is little reason to think that accommodative monetary policy plays a significant role in reducing racial inequities in the way often discussed. On the contrary, it may well accentuate inequalities for extended periods.

Keywords: monetary policy, racial inequality, income distribution, wealth distribution, wealth effects

JEL Classification: E40, E52, J15


Gratitude facilitates obedience: New evidence for the social alignment perspective

Tong, E. M. W., Ng, C.-X., Ho, J. B. H., Yap, I. J. L., Chua, E. X. Y., Ng, J. W. X., Ho, D. Z. Y., & Diener, E. (2020). Gratitude facilitates obedience: New evidence for the social alignment perspective. Emotion, Feb 2021. https://doi.org/10.1037/emo0000928

h/t David Schmitt  worm-grinder studies...the saga continues

Abstract: We report four studies that tested the hypothesis that gratitude increases obedience. Four experimental studies (N = 623) found that participants who were induced to feel gratitude obeyed to a greater extent a command to grind worms in a grinder than those feeling neutral. These novel findings demonstrate that gratitude can encourage obeying instructions to exact physical harm, violating moral principles of care. Grateful participants obeyed both benefactors and nonbenefactors. Induced happiness and admiration did not produce the same effect and we found evidence using a manipulation-of-mediator method that the need for social harmony played a mediating role. The findings suggest that gratitude can make a person more vulnerable to social influence, including obeying commands to perform an ethically questionable act.


By making information retrievability salient, Internet search reduces the likelihood of information being stored in memory; & searching online leads to the misattribution of online information to internal memory, masking learning deficits

Information without knowledge: the effects of Internet search on learning. Matthew Fisher, Adam H. Smiley & Tito L. H. Grillo. Memory, Feb 8 2021. https://doi.org/10.1080/09658211.2021.1882501

Abstract: The Internet has radically shifted how people access information. Instead of storing information internally, increasingly, people outsource to the Internet and retrieve it when needed. While this is an efficient strategy in many ways, its downstream consequences remain largely unexplored. This research examines how accessing online information impacts how people remember information in a learning context. Across five experiments, participants studied for a quiz either by searching online to access relevant information or by directly receiving that same information without online search. Those who searched the Internet performed worse in the learning assessment, indicating that they stored less new knowledge in internal memory. However, participants who searched the Internet were as confident, or even more confident, that they had mastered the study material compared to those who did not search online. We argue that, by making information retrievability salient, Internet search reduces the likelihood of information being stored in memory. Further, these results suggest that searching online leads to the misattribution of online information to internal memory, thus masking the Internet-induced learning deficits.

KEYWORDS: Memorymetacognitionlearningtechnology & cognition


People can know how their relationship partners make them feel, but, because they often desire to see their relationship partners in a positive light, they may avoid accessing these feelings

Hicks, L. L., McNulty, J. K., Faure, R., Meltzer, A. L., Righetti, F., & Hofmann, W. (2021). Do people realize how their partners make them feel? Relationship enhancement motives and stress determine the link between implicitly assessed partner attitudes and relationship satisfaction. Journal of Personality and Social Psychology, 120(2), 335–369. https://doi.org/10.1037/pspi0000247

Abstract: Do people realize the evaluative feelings that are spontaneously activated by their partner? If so, do they use those evaluations when judging their romantic relationships? To answer these questions, we investigated the association between automatic partner attitudes and judgments of relationship satisfaction in 7 studies. Study 1 was a meta-analysis of 86 correlations that revealed a very weak association between implicitly and explicitly assessed relationship evaluations, and Studies 2a–2c revealed that people failed to accurately report their automatic partner attitudes even when specifically asked to do so. Consistent with the idea that such inaccuracy emerged in part because motivational factors led people to override their automatic attitudes, Studies 3 and 4 demonstrated that automatic partner attitudes better aligned with relationship judgments when people were incentivized with money (Study 3) and had dissolved their relationship (Study 4). Nevertheless, consistent with the idea that overriding automatic attitudes requires the opportunity to deliberate, Studies 4 and 5 demonstrated that automatic partner attitudes better aligned with relationship judgments when people experienced more stress at the daily level (Study 4) and yearly for two years (Study 5). In Study 5, the interaction between stress and automatic attitudes emerged controlling indicators of negativity and was further moderated by relationship enhancing motivations among wives. These studies (a) help explain why automatic partner attitudes predict self-reported relationship satisfaction over time and (b) provide support for theories of social cognition suggesting that people have access to implicitly assessed attitudes that is obscured by motivations and opportunities to deliberate.